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The deletion of PNPLA2 in adipocytes resulted in reduced PPAR activity and expression of target genes, including lower UCP1 protein levels and when exposed to cold, mice were cold sensitive (140)

IMiDs are able to induce NKcell activation, and lenalidomide and pomalidomide also upregulate CD38 on MM cells, resulting in the synergistic enhancement of the cytotoxic effects of CD38 antibodies

Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

*Nutrients*, 9(4), 339