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References: Pimentel M, Lembo A, Chey WD, et al

Zwirner, S

Therapy decisions are informed by clinical evaluation and, when required, laboratory data to ensure antioxidant support aligns with the individuals physiological demands rather than being applied generically

The absorption of glutathione from the gastrointestinal tract has been recently investigated

This has noticeably been the case for synthetic oleanane triterpenoids that enhance NRF2 activity: these agents can be antioxidative and cytoprotective at low doses, but be pro-oxidative and cause DNA damage and apoptosis at higher doses (59,60)

doi: 10.1016/S0092-8674(00)81750-X 61 GuoF.PanF.ZhangW.LiuT.ZuberF.ZhangX.et al