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The bold indicates are abnormal findings PIGD Postural instability gait disturbance, PwPD Patients with Parkinsons disease, HC Healthy controls, MH Minor hallucinations, UPDRS-III Unified Parkinsons Disease Rating Scale part III, MMSE Mini-mental status examination, NC No statistically significant correlation Non-motor clinical correlates of Vit B12 deficiency in PD More extensive research investigated the non-motor aspects of PD directly linked to HHcy rather than focusing of Vit B12 deficiency itself

Recent studies revealed that some well-known antioxidant and anti-inflammatory substances such as plant flavonoids may counteract these deleterious changes by modulating activity of certain genes, reducing glial inflammation and inhibiting production of neurotoxins [51, 52]

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Binding analysis of Cys102 presented several challenges in this study

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