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Response to treatment with GH therapy has been poor and one child treated with recombinant human IGF-I did not improve height after 1 year of treatment
In accordance to the ACMG criteria, the variant was classified as variant of uncertain significance (VUS) [13]
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A20 knockout mice die prematurely due to severe multiorgan inflammation, whereas mice that lack A20 expression in specific immune cell types develop experimental inflammatory diseases, which closely mimic human conditions (Ma and Malynn 2012)
2005;5(6 Suppl):267S-279S
