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(157) have reviewed forty one articles including major RCTs that have studied the effect on NAC on respiratory conditions including chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis, chronic bronchitis and cystic fibrosis with respect to the side effects of NAC at doses between 600 mg per day to 3,000 mg per day

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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Nikoo M, Radnia H, Farokhnia M, Mohammadi M-R, Akhondzadeh S

Frank JT

As a mucolytic, NAC targeted an unmet need at the time when various treatment modalities such as vasoconstrictors, bronchodilators, surfactants, antibiotics, antihistamines, and proteolytic enzymes were being used for broncho-pulmonary ailments