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doi: 10.1038/536143a

Sleep deprivation depended on the rats aversion to water, as rats rarely enter water spontaneously

Abbreviations ALP: alkaline phosphatase ALT: alanine aminotransferase AST: aspartate aminotransferase CKD: chronic kidney disease GGT: gamma glutamyl transpeptidase HGF: hepatocyte growth factor HPP: hypophosphatasia NSHA: nonspherocytic hemolytic anemia PLP: pyridoxal 5-phosphate TNSALP: tissue-nonspecific alkaline phosphatase Declarations Acknowledgement The support of the Herman Lopata Chair in Hepatitis Research is gratefully acknowledged

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Nature 425 , 191196 (2003)

Rather than mimicking GHRH, it binds to the growth hormone secretagogue receptor (GHSR-1a) the same receptor your body's own hunger hormone, ghrelin, acts on