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EGCG can suppress EAE by lowering neuronal damage and brain inflammation

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Irie K, Tomofuji T, Tamaki N, Sanbe T, Ekuni D, Azuma T, et al

Importantly, diabetic and non-diabetic PD subjects show significant differences in SN and striatum denervation or cortical cholinergic denervation, as assessed by PET imaging

The VN can capture alterations in the gut microbial ecology and transmit these to the central nervous system, which will trigger adaptive or maladaptive responses the latter potentially leading to gastrointestinal diseases or neurodegenerative diseases (270)

Frontiers in Neuroscience

Foye's Principles of Medicinal Chemistry
