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Of these articles, 155 were selected, summarized, and critically discussed to provide a comprehensive review
Kirkland WD, Jones RW, Ellis JR et al
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Furthermore, given the limited and heterogeneous evidence base, together with dose-dependent adverse effects and reported cardiac safety signals, high-dose NAC or GSH should not be used routinely as disease-modifying therapies in PD outside clinical trials
(October 2007)
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