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After two weeks, the continuation dose should be increased to 53 mg once daily if the QT interval [116] corrected by Fridericia's formula (QTcF) is less than or equal to 450 ms

The Effect of Copper Oxide Nanoparticles on Hepatic and Renal Toxicity in Domestic Rabbits. Journal of Nanostructures 14: 150155

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While dietary contributions typically account for 10%20% of total body CoQ10, this proportion increases in individuals with impaired biosynthesis, such as those with genetic mutations in COQ genes (Kuang et al., 2025)

doi: 10.2337/diabetes.51.2.347 107 SenaLALiSJairamanAPrakriyaMEzpondaTHildemanDAet al

33 Metabolomics and statistical analyses These analyses were performed as described 36 and are extensively reported in the Online Supplementary Methods