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In some embodiments, the otic formulation or composition comprises about 0.03% by weight of the cholesterol

Moreover, microglia, the predominant immune cells found in the brain, along with astrocytes and oligodendrocytes, albeit to a lesser degree, are linked to the degeneration of neurons in PD (Badanjak et al., 2021

These nanocarriers included API solid lipid nanoparticles, API liposome nanocapsules, API-casein nanoparticles, and API-loaded mesoporous silica nanoparticle solid dispersions (AP-MSN)

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204 Disruption of PCD pathways is a common feature in cancer, enabling cancer cells to evade death and sustain uncontrolled proliferation, thus contributing to tumorigenesis and progression