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doi: 10.1007/s10555-007-9041-7
The jump from "shows promise in mice" to "works in humans" is substantial and has derailed countless therapeutic candidates
activation of the Akt/PI3K pathway, and resulting GSH induction [380]
Singh AB, Kan CFK, Kraemer FB, Sobel RA, Liu J
Carbonic anhydrase III has two reactive sulfhydryls that are subject to conversion to cysteine sulfinic acid or cysteic acid in the presence of H 2 O 2 , peroxy radicals or hypochlorous acid (HOCl)
