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[DOI] [PMC free article] [PubMed] [Google Scholar] Fengyun, C
However, treatment of mice with this compound did not affect the clinical score in a significant manner, whereas it produced significant reduction in paw volume at its peak, eg

Serum selenium and glutathione peroxidase-3 activity: biomarkers of systemic inflammation in the critically ill

This means that lower doses may achieve the desired therapeutic effect, thereby reducing systemic side effects and enhancing treatment efficacy (Agrawal et al., 2018)
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Considering that the N-terminal of a protein is very important for its half-life, the first N-terminal 11 residues of Fh8 were named the H sequence and were initially suggested to play a key role in the stability and production of the entire Fh8 protein
