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Daratumumab (Janssen Pharmaceuticals) is the first high-affinity CD38-targeting Ab to be approved by the FDA and EMA as a monotherapy for relapsed/refractory MM (RRMM) [65]

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This does not mean the shot alone causes weight loss, but it can support the systems involved in turning food into usable fuel

Because injections do not rely on stomach acid or intrinsic factor, a much larger and more reliable share of the dose reaches your bloodstream, even when gut absorption is poor

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