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[DOI] [PubMed] [Google Scholar] 8.Sikiric P, Seiwerth S, Brcic L, et al
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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State
What they found: Preventive administration: 70 to 85 % reduction in ulcer area Therapeutic administration: 60 to 75 % reduction And now the most interesting part: 10 ng/kg worked just as well as 10 g/kg Why it matters: If the molecule worked in a stoichiometric way (= simply blocking something piece by piece), a higher dose would necessarily produce a larger effect
Journal of Endocrinology and Metabolism , 3(1-2), 7-15
