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Flockhart, M

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Aug 2022;73(1):e12801

In most of our registries, males contribute to 67%70% of the population, whereas the distribution is nearly 50:50 in high-income countries

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Preclinical studies investigating isolation-induced psychopathology suggest that these affective changes may involve endocannabinoid system dysregulation in limbic and cortical regions highlighting the potential therapeutic value of modulating endocannabinoid tone ( Consistent with previous reports ( This study was conducted exclusively on male mice as a pilot experiment to characterize preliminary neurobehavioral outcomes before expanding the investigation to both sexes