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PLoS One 9: e95759, 2014

On one hand, TMAO and its precursors are found in foods eaten regularly in heart-healthy Mediterranean diets, particularly seafood
The drawback of high TMAO: A number of studies link higher plasma TMAO levels to an increased relative risk of thrombosis (heart attack, stroke)

BMC Evol

Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3

Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, et al