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Another commonly used assay employs horseradish peroxidase, which uses HO to oxidize scopoletin into a non-fluorescent product

This broad therapeutic window suggests the peptide operates differently from conventional medications with narrow dosing requirements

To assess the importance of lipidation modification to Cagri, pharmacological comparison of Cagri and its non-lipidated backbone (CagriBB) was undertaken using a cAMP response element (CRE)-reporter assay

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