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Description
Concretely, GPX4 uses GSH as the substrate to reduce phospholipid hydroperoxides (PLOOHs) to hydroxyl derivatives (PLOHs), and oxidizes GSH to GSSH, therefore alleviating the damage of oxidative stress to tumor cells (Stockwell, 2022)
The purpose here is to provide a brief overview of some of the important aspects of glutathione metabolism as part of this special issue that will provide a more comprehensive review of the state of knowledge regarding this essential molecule
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References Janeway, C
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GYIK (Gyakori Krdsek s Vlaszok) glutation Milyen formban rhet el a glutation
Acknowledgments Authors express special thanks to Ken Rory and many other colleagues of the Academiacs International network ( accessed on 14 May 2021) for helpful discussions and inspiration
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10.1016/j.mtbio.2022.100522 45 JurkowskaH.WrbelM
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