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This lends support to the notion that the main physiological roles of these enzymes is in regulating the concentrations of lipid peroxides that are poorly or not metabolized by catalase or APX, or in peroxide sensing

Identification and characterization of human ethanolaminephosphotransferase 1

However, there are still several outstanding issues in this area that have not been adequately addressed

Hassan HM, Scandalios JG

While promising, these findings are limited to animal studies, and clinical research is needed to determine whether fisetin may serve as a safe, effective, and non-hormonal therapeutic option for women with PCOS

& Young, B