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Description
Niacinamide works best between pH 5 and 7

In addition to its antioxidant effects and promotion of glutathione synthesis, its also a powerful anti-inflammatory compound that can reduce inflammatory signaling in cells
,

Multidrug resistance proteins (MRPs, ABCCs): Importance for pathophysiology and drug therapy

FASEB J 29:38633875

1) in the journal eLife