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after 7 days of exposure, it also caused a significant reduction in cardiac shortening fraction only in the GPx1-deficient mice, an indication that GPx1 deficiency sensitized mice to angiotensin II-mediated left ventricular dysfunction [42]

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10.1096/fj.06-7859rev 67 KaiafaG

To date, five variants of GlyT1 (GlyT1a, GlyT1b, GlyT1c, GlyT1d, and GlyT1e) and three variants of GlyT2 (GlyT2a, GlyT2b, and GlyT2c) have been identified and occur as a result of alternative promoter usage and/or splicing, but the relative distributions of these within the CNS have not been fully characterized [21]