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In the PPMI cohort, amongst patients with sporadic PD (negative for GBA mutations), patients with higher CSF glucocerebrosidase-to-sphingomyelin ratios showed faster cognitive decline over 3 years, although the ratio did not show significant longitudinal changes 191

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Enhanced cystine uptake and GSH biosynthesis bolster GPX4 activity, thereby suppressing ferroptosis and promoting tumor growth and resistance to therapy (53)

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Macrophages: targets for next-generation cancer immunotherapy

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Nutrition in Clinical Care: An Official Publication of Tufts University

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