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Also, ED caused by cigarette smoke is protected by glutathione-S-transferase P (GSTP) [139]

Additionally, we assessed mitotic clonal expansion (MCE), which has been shown to support early adipogenesis in both murine and human preadipocytes, by measuring using 5-bromodeoxyuridine (BrdU) incorporation 24 h after induction of adipogenesis

These limitations dont invalidate the positive safety findings but do suggest that comprehensive medical supervision remains appropriate for anyone using AOD-9604, particularly for off-label applications or extended treatment periods

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