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Experiments performed in differentiated SH-SY5Y neuroblastoma cells have shown that exposure to PS-NPs downregulates expression of the CI subunit NDUFB8, leading to diminished basal and maximal oxygen consumption rates alongside increased proton leakagefurther confirming mitochondrial CI dysfunction 32

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Metabolomics studies small molecule metabolites, offering key clues for discovering cancer treatment targets (Schmidt et al., 2021)

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The tripeptide GSH is one of the most important endogenous antioxidants

Role of cAMP and cGMP signaling in brown fat