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Several emerging approaches are gaining traction in preclinical research settings: Raman spectroscopy: Surface-enhanced Raman spectroscopy (SERS) enables label-free detection of glutathione in biological samples

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This is the "conjugation" mechanism

The authors concluded that 10 M of FLX significantly reduced MGMT concentrations by disrupting NF-kB/p65 signaling and, hence, sensitizing GBM cells to TMZ
