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Then, the sequences in each sample were denoised using AmpliconNoise (implemented in QIIME) with the default parameters, except that the Perseus algorithm for chimaera removal was disabled

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10.1016/bs.acr.2017.07.004 36 KrausR

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One of the earliest events associated with APAP intoxication and excessive NAPQI generation is depletion of GSH stores, both the cytosolic and mitochondrial pools (45)