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doi:10.1016/S1359-6446(02)02452-2 38

The rest of the state eventually followed suit

Inhibition of glycan shedding and leukocyte-endothelial adhesion in postcapillary venules by suppression of matrixmetalloprotease activity with doxycycline
Once reconstituted, store the solution in the refrigerator and use it within a few weeks to maintain its effectiveness
doi: 10.1023/a:1017921110363

They're compensating for the biomechanical issues that caused the problem in the first place
