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Pre-treatment with IGF-1 signal pathway specific inhibitors such as picropodophyllin, LY294002, and rapamycin attenuated EE induced myotube hypertrophy and MyHC isoform overexpression

1,2,6,12,14,160163 An increase of 20% in LSM by TE during follow-up is associated with a 50% increase in the risk of liver decompensation and liver-related mortality in patients with compensated advanced MAFLD