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Only in the case of PD was there a reduction in scores in the Vitamin-B6 group that was unlikely to be explainable by placebo effects or regression to the mean

doi: 10.2147/DDDT.S82030

Signs and symptoms of vitamin B12 deficiency can include fatigue, pale skin, headaches, shortness of breath, fast heartbeat, gastrointestinal issues, mouth inflammation, paresthesias (abnormal sensations), decreased cognitive ability, depression, muscle weakness, imbalance and incoordination, vision problems, and erectile dysfunction

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PMID: 29998800 Malinda KM, et al
