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Funding This work was supported by the National Natural Science Foundation of China (22171230, 82001956), the National University of Singapore (NUHSRO/2020/133/Startup/08, NUHSRO/2023/008/NUSMed/TCE/LOA, NUHSRO/2021/034/TRP/09/Nanomedicine, NUHSRO/2021/044/Kickstart/09/LOA, 23-0173-A0001), the National Medical Research Council (MOH-001388-00, CG21APR1005, MOH-001500-00, MOH-001609-00), the Singapore Ministry of Education (MOE-000387-00, MOET32023-0005), the National Research Foundation (NRF-000352-00), the Project of Science and Technology of Social Development in Shaanxi Province (2023YBSF-151 and 2021SF-120), and the 2023 Hangzhou West Lake Pearl Project Leading Innovation Youth Team Project (TD2023017)