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As discussed above, elevated serum B12 is often a marker of underlying conditions rather than a direct consequence of supplementation

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These findings are summarized in a Cochrane review (238) including one study with high-dose Zn intake [(305), 10 mg/day] and 4 studies with low (currently recommended) dose were included (306, 307)

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Cellular uptake For cellular uptake, wild-type MCF-7 (10,000 cells) were incubated with Cy5.5-labelled B-017 (4.4 M) or Cy5.5-labelled negative control peptide for 1 h and visualised using the EVOS FL microscope (ThermoFisher Scientific)

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