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We are seeing more cases of vitamin B12 deficiencies, even in men and women who adhere to healthy eating and lifestyles

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Its most cited proposed mechanism is an increase in brain-derived neurotrophic factor (BDNF) and its receptor TrkB, alongside modulation of monoaminergic systems (dopamine, serotonin) and the melanocortin pathway [3] [4]

Blood tests can be particularly helpful in identifying gaps such as low vitamin D, B12, or magnesium levels, enabling targeted supplementation

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PMID: 27771752