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Activated KRAS-GTP can recruit rapidly accelerating fibrosarcoma (RAF), a serine/threonine-specific protein kinase, from the cytoplasm to the plasma membrane, induce conformational changes in RAF and promote the activation of RAF by homologous or heterologous dimerization 44

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Interleukin-6 cytokine: an overview of the immune regulation, immune dysregulation, and therapeutic approach
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