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Description
Of these, 35 were preclinical animal studies and only one represented a human clinical investigation

Ursodeoxycholic acid (UDCA) has been found ineffective for pruritus relief in primary sclerosing cholangitis and primary biliary cholangitis but is recommended for treating pruritus in intrahepatic cholestasis of pregnancy only, at doses of 1015 mg/kg/day, divided into 23 doses

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10.2174/156720510793611592 Curr
Effective therapeutic drug delivery by GALA3, an endosomal escape peptide with reduced hydrophobicity

e Ec Grx1= Escherichia coli glutaredoxin 1 f slund, F