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conducted a questionnaire survey to gauge the cognitive function of seniors 60 years of age and older in the Huangshi community in order to better understand the prevalence of mild cognitive impairment (MCI) and its influencing factors (93)

The control group was recruited from a Primary Health Care Service and composed of 18 healthy volunteers matched by age and gender

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Although melasma is a multifactorial skin disorder, however, sun-exposure and genetic predisposition are considered as the main etiologic factors in melasma occurrence

For example, in one study [121], high RASSF1 methylation of the CpG island in the RASSF1A promoter was found in all patients with PDTC and in 78% of ATC cases, but it was relatively low in differentiated thyroid cancer [121]

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