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CFTR -/- mice had enhanced intracellular Ca 2+ flux in response to T cell receptor (TCR) activation on T effectors cells, higher interleukin (IL) 4, IL-13, IgE and IgG1, this prominent Th2 bias correlated with higher nuclear NFAT level than their wild type control littermates (CFTR +/+ )

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doi: 10.1038/mp.2012.90

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Lack of the Nlrp3 inflammasome improves mice recovery following traumatic brain injury

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However, its not as anabolic as protein or creatine

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