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Y., & Choi, S

2.5 Combination therapy inhibits the growth of Th- MYCN mouse NB spheroids To assess the antitumor potential of the dual and triple drug combinations in a more physiological model than cell lines, we used a 3D spheroid model of a transgenic mouse that overexpresses MYCN under the control of the tyrosine hydroxylase (Th) promoter
Bonnett LJ, Powell GA, Tudur Smith C, Marson AG

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Current Research on 5-Amino-1MQ 5-Amino-1MQ has been examined in laboratory research studies as an inhibitor of NNMT, an enzyme associated with cellular metabolic pathways

Antivitamin B12 Inhibition of Human B12-Processing Enzyme CblC Crystal Structure of Abortive Ternary Complex with Cosubstrate Glutathione
