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Since most PK-deficient patients are compound heterozygous for two different mutations, rather than homozygous for one, several different tetrameric forms of PK-R may be present, each with distinct structural and kinetic properties

To understand why GP practices sometimes differ from these guidelines and what that can mean for you, you can read more about the nuances of B12 guidelines

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Roy carefully calibrates your dose between 1,400mg and 2,400mg per session

Acta Pharmacologica Sinica, 45 , 115

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