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This include lack of consideration for the high lipid solubility of cannabis metabolites which helps them to persist in fatty tissues, therefore they may be detected in the urine weeks after the initial use ( Probable Mechanism Associated With Cannabis-Mediated Neurovascular Diseases It is evident from various studies that, consumption of cannabinoids through inhalation and combustion, is associated with the occurrence of cerebral infarcts (Wolff and Jouanjus, 2017)