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Inhibition of DPP1, the key protease that catalyzes maturation of NSPs, is a potential approach to this objective

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Research efforts are also focused on understanding how variations in experimental design, concentration, and molecular stability may affect compound behavior across different in vitro systems

Though functional roles of the VGF peptides detected here remain to be established, consistent changes in VGF abundance across proteoforms between diagnostic classes in the present study, as well as previous literature, suggest clear roles of VGF peptides in cognitive functioning 15

When collagen breaks down, fragments of it called matrikines bind to fibroblast receptors and trigger new collagen production as a repair signal

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