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Pharmaceutical Research, 29 (6), 14251434

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High levels of HO inactivate protective peptides like ACTH and -MSH, while decreasing enzyme activities like methionine sulfoxide reductase, consequently intensifying oxidative damage and accelerating melanocyte death 46

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275 : 3284632853 Kokame K, Kato H and Miyata T (1996) Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis