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The system designed to protect patients has instead created a landscape where: The pathway with physician oversight, vetted compounding pharmacies, and certificates of analysis is being systematically narrowed The pathway with no purification standards and no accountability is the most accessible one In the final article of our Peptides & Biological Signaling series, I break down how the Category 1/2/3 regulatory framework actually works, why restriction doesn't reduce demand (it relocates it), what the VIP protection story reveals about what responsible evidence-building costs, and what this controversy is really about at the level of institutional biology

These injections are not included in NICE guidelines for weight management, which instead emphasise evidence-based interventions including dietary modification, increased physical activity, behavioural therapy, and in appropriate cases, pharmacological treatments (such as orlistat or semaglutide) or bariatric surgery

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