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Due to skin hypoxia (small concentration of oxygen in the skin), consumption is described by a linearized Michaelis-Menten law and we get: where is the 2D Laplacian (see the Supplementary), n and c are now the concentration averaged along the epidermis depth, n s is a typical nutrient concentration necessary to maintain the homeostatic state of the skin

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elegans , which is based on the encapsulation of the proteins of interest within cationic lipid vesicles, prior to their administration to worms

These studies not only deepen our understanding of the role of CEBPA in hepatocellular carcinoma, but also further confirm its great potential as a potential therapeutic target

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All experiments in the present work have been performed using this incubation time, unless otherwise stated