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The structure of the enzyme in complex with glutathione has been determined to high resolution (1.9 to 2.2 A) in three different crystal forms and at two different temperatures (100 and 288 K)

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10.1097/MOL.0b013e32833f9c37 42 RussellA

SIRT3 also deacetylates targets such as the chaperone protein Hsp10 and the LON protease, involved in the UPR mt process 98

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