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Additional support was provided by the Division of Intramural Research at the National Institute on Deafness and Other Communication Disorders, NIH/NCRR extramural research facilities construction (C06) Grants C06 RR015455 and C06 RR14516 from the National Center for Research Resources, and the MUSC Initiative for Maximizing Student Diversity (IMSD) Program

Trxs and Grxs are thiol-disulfide oxidoreductases, whereas Prxs mainly reduce peroxides

Consequently, this leads to a reduction in TGF- expression, inhibition of collagen synthesis (specifically Col1 and Col3), and attenuation of myofibroblast differentiation, as indicated by lowered -SMA levels

It is a major public health issue with a high incidence, resulting in disability and death, with millions of new cases reported annually [405]

, Rhaume, M.A

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