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Description
While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13

It calms inflammation through a mechanism similar to aspirin, which is the parent molecule of salicylic acid, reducing redness around active lesions

AOD9604 appears to stimulate proteoglycan and collagen synthesis in chondrocytes through growth factor signaling pathways distinct from its lipolytic mechanism, supporting cartilage matrix repair in joint models

Next steps in mechanisms of inflammaging

*Correspondence: Maria R

Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial
