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As a result, off-target effects and systemic toxicity are significantly minimized

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Bile acid absorption in the ileum is an active process involving the nuclear farnesoid X receptor (FXR), which can be phosphorylated by AMPK, decreasing FXR transcription

It is important to note that, unlike healthy individuals, patients with AD exhibit a distinct protein profile among those adsorbed onto nanoparticle surfaces across various platforms (Corbo et al., 2021)
These keystone species are responsible for producing short-chain fatty acids (SCFAs) like butyrate, which help keep the gut lining healthy and suppress inflammation

On a highway to the brain: a review on nose-to-brain drug delivery using nanoparticles
