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Rohatgi P, Swisher S, Correa A, Wu TT, Liao X, Komaki R, Walsh G, Vaporciyan A, Rice DC , Roth JA, Ajani JA

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Chondrocytes, the only cellular component of cartilage, maintain the dynamic equilibrium of the extracellular matrix (ECM) through precise regulation of collagen type II and matrix-degrading enzyme secretion ( In mouse models of OA, typical characteristics of ferroptosis have been observed in chondrocytes, including abnormal iron metabolism, lipid peroxidation, and mitochondrial dysfunction (Sun et al., 2021)

Small interfering RNA: discovery, pharmacology and clinical development-an introductory review

Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients

Intriguingly, high-altitude natives in regions like the Himalayas and the Andes possess unique gut microbial profiles characterized by enrichment of fiber-fermenting taxa and short-chain fatty acids (SCFAs)-producing bacteria, which are hypothesized to contribute to enhanced hypoxic tolerance (Quagliariello et al., 2019)