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Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase

(2011), which established that the contents of glutamate and glutamine in cultured astrocytes increase by 50% in the presence of aspartate at a concentration of 100 M, but not in the presence of alanine or leucine

Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

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However, the studies mentioned above highlight its significance in AS and offer new insights for investigating the pathological mechanisms of AS through ferroptosis

Farias ICC, Mendona-Belmont TF, da Silva AS et al (2018) Association of the SOD2 polymorphism (Val16Ala) and SOD activity with vaso-occlusive crisis and acute splenic sequestration in children with sickle cell anemia