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Brain behavior Immun (2016) 52:12031

Senolytic drugs specifically target senescent cells damaged cells that accumulate with age and lead to chronic inflammation and age related diseases like cardiovascular conditions, osteoarthritis and neurodegenerative disorders by targeting and eliminating them through selective cell removal

Plant and Cell Physiology 60, 21672179

J Pediatr 96 : 893897

With equal low affinity and no selectivity, each neurotrophins can bind to the pan-neurotrophin receptor p75 (p75NTR), and with high affinity to the tropomyosin-related kinase (Trk) receptor family: with NGF binding to TrkA, BDNF and NT4/5 to TrkB and NT3 to TrkC

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